Uric Acid and Left Ventricular Hypertrophy

Uric acid and left ventricular hypertrophy in Japanese men.

BACKGROUND Experimental studies have reported that allopurinol protects hypertensive rats from left ventricular hypertrophy (LVH) with negligible effects on blood pressure (BP). Uric acid (UA) was thought to induce cardiomyocyte growth and interstitial fibrosis of the heart, partly via activation of the renin-angiotensin system. In the present study, the relationship between serum UA levels and...

Gender-related association of serum uric acid and left ventricular hypertrophy in hypertension.

BACKGROUND The aim of the present study was to determine whether sex differences contribute to the association of serum uric acid and left ventricular hypertrophy in individuals with hypertension. METHODS AND RESULTS Seventy participants with essential hypertension (34 men, 36 women; 54.4 +/- 1.6 years old) were enrolled to undergo echocardiography to calculate the left ventricular mass index...

echocardiographic assessment of inappropriate left ventricular mass and left ventricular hypertrophy in patients with diastolic dysfunction

background: early diagnosis of left ventricular mass (lvm) inappropriateness and left ventricular hypertrophy   (lvh) can result in preventing diastolic left ventricular dysfunction and its related morbidity and mortality. this study was performed to determine if diastolic dysfunction   is associated with lvh and inappropriate lvm. methods: one hundred   and twenty five uncomplicated hypertensi...

Left Ventricular Hypertrophy Familial Predisposition of Left Ventricular Hypertrophy

METHODS Echocardiographic and anthropometric measurements were performed in 2,293 individuals who participated in the echocardiographic substudies of population-based MONICA Augsburg surveys. In addition, a total of 319 siblings of survey participants with echocardiographic evidence of LVH were evaluated. The risk of these siblings to present with LVH or abnormal LV geometry was estimated by co...

Left ventricular hypertrophy.